The timeliness of the topic at the national and global scale, is only matched by its political, economic and social relevance. The sustainability of urban areas is assailed by a combination of threats never seen before. At a time when—for the 1st time in history—more than 50% of humans reside in cities, those looming threats demand multidisciplinary approaches both to understand them better and to provide sensible solutions that mitigate the negative effects while amplifying the potential benefits. This class addresses those dimensions (economic, social, environmental, and political) as well as their interactions; it offers a framework under which the potential or already observed impacts are quantified and analyzed; and it surveys the policies implemented around the world. Although there are no explicit pre-requisites, students are expected to have a cursory understanding of economics and basic analytics.